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Nitric Oxide (NO)
Industry News

Nitric Oxide (NO)

2026-04-10

Product Overview

Nitric oxide (NO)is a versatile specialty gas serving both semiConductor manufacturing and medical applications. In the electronics industry, it is used as a dopant source, oxidation agent, and calibration gas for emissions monitoring. In healthcare, NO is a therapeutic gas for pulmonary hypertension, requiring the highest purity standards .

According to TECHCET data, the global electronic specialty gas market reached $4.64 billion in 2025, with reactive gases like NO requiring specialized cylinder handling and passivation treatments. The Asia-Pacific region accounts for approximately 74.4% of global semiconductor gas consumption .


Technical Specifications

Parameter Electronic Grade Medical Grade
Purity ≥99.5% ≥99.0%
Nitrogen Dioxide (NO₂) <10 ppm <5 ppm
Nitrous Oxide (N₂O) <50 ppm <10 ppm
Moisture (H₂O) <10 ppm <5 ppm
Carbon Dioxide (CO₂) <50 ppm <10 ppm

Applications

Semiconductor Manufacturing

  • Doping source for silicon oxidation processes

  • Calibration gas for emissions monitoring systems

  • Research applications in III-V compound semiconductor processing

Medical & Healthcare

  • Inhaled nitric oxide therapy for pulmonary hypertension

  • Neonatal respiratory distress syndrome treatment

  • Calibration of medical gas analyzers

Environmental Monitoring

  • Calibration standard for CEMS and ambient air monitors

  • Stack emission testing for NOx compliance


Safety & Handling

NO  is a toxic, oxidizing gas that reacts with oxygen to form nitrogen dioxide (NO₂):

  • Requires specialized cylinder treatments to prevent decomposition

  • Stainless steel or aluminum cylinders with passivated internal surfaces

  • Store in well-ventilated gas cabinets with continuous monitoring

  • Dedicated toxic gas detection systems required

  • Regular calibration of monitoring equipment using certified reference standards


Cylinder Preparation

Due to NO 's reactive nature, specialized handling is required:

  • Passivated cylinder internal surfaces

  • Stainless steel diaphragm valves

  • Concentration verification throughout shelf life

  • Periodic recertification for reactive gas standards

  • Specialized analytical methods for stability testing


Quality Assurance

Chengdu Hongjin Chemical Co., Ltd. provides high-purity nitric oxide with:

  • Certificate of Analysis (COA) for each batch

  • Traceability to national metrology standards

  • ISO 9001:2025 certified quality management

  • Specialized cylinder handling for reactive gases

  • Technical support for medical and calibration applications


References:

  • TECHCET Electronic Specialty Gases Market Report, 2026

  • Pharmaceutical guidelines for medical nitric oxide